(S)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one TFA CAS 324548-43-8 (free base)
| CAS No. | 324548-43-8 (free base) |
| Molecular Formula | C13H18ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(S)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one TFA (CAS 324548-43-8 (free base)) is a high-purity analytical reference standard with the molecular formula C13H18ClNOC2HF3O2 and a molecular weight of 353.76 g/mol.
Based on its molecular formula C13H18ClNOC2HF3O2, (S)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one TFA contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 353.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one TFA meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18ClNO C2HF3O2 |
| Molecular Weight | 353.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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